Radiation Dosimetry of Rubidium-86

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Distribution of rubidium-86 accumulated in the rabbit lens.

he in vitro accumulation of rubidium86 has provided a simple and convenient method for evaluating cation transport by the rabbit lens. The accumulation of rubidium occurred against a concentration gradient, was temperature dependent, demonstrated saturation kinetics, and was inhibited "competitively" by potassium. The accumulation was also inhibited by ouabain in concentrations as low as 10~ M....

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Accumulation of rubidium-86 by the rabbit lens.

Rabbit lenses incubated in vitro in potassium-free Tyrode's solution for 4 hours accinnulated trace amounts of Rb-86 to a concentration averaging 18 times that of the incubation medium. The uptake of Rb-86 was temperature dependent and required calcium. In the presence of glucose it was inhibited by iodoacetate, ouabain, or digoxin, but not by dinitrophenol, fluoroacetate, or anaerobiosis. The ...

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ژورنال

عنوان ژورنال: Nature

سال: 1955

ISSN: 0028-0836,1476-4687

DOI: 10.1038/175034a0